abstract：:In this study the baroreflex sensitivity of conscious, juvenile, spontaneously hypertensive rats (SHRs) was compared. The study population consisted of 19 eight-week-old male SHRs. The baroreflex sensitivity was quantified as the derivative of the variation in heart rate (HR) and the variation of mean arterial pressur...

journal_title：Cardiovascular journal of Africa

authors： Valenti VE,De Abreu LC,Colombari E,Sato MA,Ferreira C

更新日期：2011-01-01 00:00:00

abstract：:This study examined the effects of quercetin on spontaneously contracting portal veins isolated from healthy young adult male and female Wistar rats (250-300 g). Quercetin (10(-7)-10(-4) M) always produced significant biphasic effects, comprising an initial brief stimulant effect (rise in basal tone), followed by a su...

journal_title：Cardiovascular journal of Africa

authors： Chiwororo WD,Ojewole JA

更新日期：2010-05-01 00:00:00

abstract：:Activation of AMP-activated protein kinase (AMPK) results in glucose transporter 4 (GLUT4) translocation from the cytosol to the cell membrane, and glucose uptake in the skeletal muscles. This increased activation of AMPK can be stimulated by a pharmacological agent, AICAR (5' -aminoimidazole-4-carboxamide ribonucleos...

journal_title：Cardiovascular journal of Africa

authors： Webster I,Friedrich SO,Lochner A,Huisamen B

更新日期：2010-03-01 00:00:00

abstract：:Type 2 diabetic patients treated with statins but still experiencing elevated serum levels of triglycerides (2.3 mmol/l or higher) and low HDL cholesterol (0.8 mmol/l or lower), a pre-specified subgroup, benefited from the addition of fenofibrate to their treatment regimen. Risk of cardiovascular events was reduced by...

journal_title：Cardiovascular journal of Africa

authors： Aalbers J

更新日期：2010-03-01 00:00:00

abstract：INTRODUCTION:Associations between ambient temperature and blood pressure have been demonstrated in countries where the temperature varies between the seasons. This phenomenon has been overlooked in blood pressure surveys in sub-Saharan Africa. We assessed the effect of ambient temperature on blood pressure in an adult ...

journal_title：Cardiovascular journal of Africa

authors： Kunutsor SK,Powles JW

更新日期：2010-01-01 00:00:00

abstract：:We present images of a chest CT scan of an 89-year-old man, showing an area of localised dissection in the convexity of the aortic arch. The ascending and descending aorta were not involved in the disease. The patient suffered a stroke, with severe neurological impairment. Differential diagnosis was undertaken. ...

journal_title：Cardiovascular journal of Africa

authors： Lentini S,Passari G,David A,Gaeta R

更新日期：2009-11-01 00:00:00

abstract：:This was a study of the pre-operative factors that influence quality of life (QoL) in patients with coronary artery disease and the relationship between pre-operative QoL and early outcome after coronary artery bypass surgery (CABG). Using the WHOQOL-BREF questionnaire, 283 patients who underwent isolated coronary art...

journal_title：Cardiovascular journal of Africa

authors： Najafi M,Sheikhvatan M,Montazeri A

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:To assess the influence of diabetes mellitus on early morbidity and mortality following a femoro-popliteal bypass. METHODS:Clinical data on patients subjected to a prosthetic above-the-knee femoro-popliteal bypass for atherothrombotic disease over a four-year period in the Durban Metropolitan Vascular Servi...

journal_title：Cardiovascular journal of Africa

authors： Mulaudzi TV,Robbs JV,Paruk N,Pillay B,Madiba TE,Govindsamy V

更新日期：2009-05-01 00:00:00

abstract：:Left ventricular hypertrophy is a common complication of primary hyperparathyroidism. Numerous disturbances of myocardial physiology have been described as a result of excess parathyroid hormone action. In this brief communication, another phenotype of the hyperparathyroid heart is proposed, the 'pseudo-myocardial inf...

journal_title：Cardiovascular journal of Africa

authors： Ker J

更新日期：2009-05-01 00:00:00

abstract：:We report on the case of a 65-year-old man with unstable angina due to a left anterior descending (LAD) coronary artery single aneurysm. On a beating heart, the aneurysm was partially resected and the left internal thoracic artery was grafted in situ as a patch to the LAD opening. The patient remains well and free of ...

journal_title：Cardiovascular journal of Africa

authors： Misthos P,Kokotsakis JN,Lioulias AG,Skouteli EA

更新日期：2009-03-01 00:00:00

abstract：:This review discusses the 1987 article by Wyndham, Seftel, Pilcher and Baker on familial hypercholesterolaemia (FH) and myocardial infarction (MI) in young Afrikaners, in terms of the significance at the time of publication, as well as the relevance of their findings versus current observations on hypercholesterolaemi...

journal_title：Cardiovascular journal of Africa

authors： Delport R

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:To identify case fatality rates and predictors of stroke in a private clinic in Kinshasa, Democratic Republic of Congo. METHODS:Two hundred and twelve black Africans were consecutively admitted to a clinic and prospectively assessed during the first 30 days by CT scan-proven stroke types and outcome. Univari...

journal_title：Cardiovascular journal of Africa

authors： Longo-Mbenza B,Lelo Tshinkwela M,Mbuilu Pukuta J

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:A four-amino acid deletion was identified within the alpha 2C-adrenergic receptor (alpha 2C Del322-325) that, when homozygous, increases the risk of heart failure in African-Americans nearly six-fold. We hypothesised that homozygosity for the alpha 2C Del322-325 polymorphism may be a risk factor for heart fa...

journal_title：Cardiovascular journal of Africa

authors： Du Preez J,Matolweni LO,Greenberg J,Mntla P,Adeyemo AA,Mayosi BM

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Previous studies have shown controversial results on the role of androgens in coronary artery disease (CAD). We performed this study to assess the relationship between androgen levels and selective coronary angiography (SCA) findings. METHODS:This study was conducted on 502 consecutive men who underwent SCA...

journal_title：Cardiovascular journal of Africa

authors： Davoodi G,Amirezadegan A,Borumand MA,Dehkori MR,Kazemisaeid A,Yaminisharif A

更新日期：2007-11-01 00:00:00

abstract：:We researched hypertrophic cardiomyopathy (HCM) and long QT syndrome (LQTS) as models for studying the pathophysiology of arrhythmias and hypertrophy, and in the process we have had the opportunity to compare local disease profiles with global patterns. We trawled our database entries over the past 20 years to identif...

journal_title：Cardiovascular journal of Africa

authors： Heradien M,Goosen A,Moolman-Smook JC,Brink PA

更新日期：2007-09-01 00:00:00

abstract：:Hypertension is more prevalent and severe in urban black populations compared to whites, and is associated with a greater degree of target-organ damage for any given blood pressure level. In general, compared to whites, blacks respond well to diuretics and calcium channel blockers and less well to beta-blockers and AC...

journal_title：Cardiovascular journal of Africa

authors： Lindhorst J,Alexander N,Blignaut J,Rayner B

更新日期：2007-07-01 00:00:00

abstract：:Unlike other parts of the world in which cardiomyopathy is rare, heart muscle disease is endemic in Africa. The major forms of cardiomyopathy in Africa are dilated cardiomyopathy (DCM) and endomyocardial fibrosis (EMF). Whereas DCM is a major cause of heart failure throughout the continent, EMF is restricted to the tr...

journal_title：Cardiovascular journal of Africa

authors： Mayosi BM,Somers K

更新日期：2007-05-01 00:00:00